Dr.Becky Bundy have begun development of a laboratory exercise that brings the cutting edge blood-clot busting technology into both high school biology and physics classrooms since 2014. This laboratory involves the use of rotating iron oxide rods to speed-up drug mediated blood clot dissolution, and is based on work published by our research group. For safety, and to make the lab accessible to teachers on a tight budget, she uses a blood-clot analogue made from readily available gelatin. The use of gelatin enables clot-dissolution using pineapple juice or meat tenderizer containing bromelain, which slowly liquefies the gelatin much as tissue plasminogen activator (tPA) is used to help break-up actual blood clots in stroke patients. She found the addition of rotating iron oxide particles drastically speeds up the dissolution of our gelatin clots by bromelain, much as they have been shown to speed-up actual blood clot dissolution by tPA.
Dr. Becky Bundy has been teaching AP Physics, Physics and Chemistry for 8 years, the last 7 of which have been at Madison County High School in Danielsville, GA. Becky has a PhD in Microbiology (2001) from the University of Georgia, and was a post-doctoral associate there for 5 years (in Molecular Parasitology) before becoming a high school science teacher. She is an active member of the Georgia Science Teachers Association, presenting new and exciting ideas to other science teachers as often as possible, and loves nothing more than bringing cutting edge research into her classroom to help foster her student’s love of science.